XMD-17-51 (TFA)
XMD-17-51 TFA is a pyrimido-diazepinone compound that is able to modulate protein kinases[1].
Product Specifications
CAS Number
2436579-93-8
UNSPSC
12352005
Target
AMPK; Bcr-Abl; ERK; Mps1; Polo-like Kinase (PLK) ; Trk Receptor
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Epigenetics; MAPK/ERK Pathway; Neuronal Signaling; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/xmd-17-51-tfa.html
Purity
99.46
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1N(C)C2=CN=C(NC3=CN(C4CCNCC4)N=C3)N=C2N(C)C5=CC=CC=C15.OC(C(F)(F)F)=O
Molecular Formula
C23H25F3N8O3
Molecular Weight
518.49
References & Citations
[1]WO 2014145909 A2.|[2]Yang WQ, Zhao WJ, Zhu LL, et al. XMD-17-51 Inhibits DCLK1 Kinase and Prevents Lung Cancer Progression. Front Pharmacol. 2021;12:603453.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC550362-100 1x 100 µL
CD4 (T-Helper/Inducer Cell Marker) (RIV7), CF555 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNCB0096-100 1x 100 µL
Histone H1 (AE-4), Biotin conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
