XMD-17-51 (TFA)
XMD-17-51 TFA is a pyrimido-diazepinone compound that is able to modulate protein kinases[1].
Product Specifications
CAS Number
2436579-93-8
UNSPSC
12352005
Target
AMPK; Bcr-Abl; ERK; Mps1; Polo-like Kinase (PLK) ; Trk Receptor
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Epigenetics; MAPK/ERK Pathway; Neuronal Signaling; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/xmd-17-51-tfa.html
Purity
99.46
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1N(C)C2=CN=C(NC3=CN(C4CCNCC4)N=C3)N=C2N(C)C5=CC=CC=C15.OC(C(F)(F)F)=O
Molecular Formula
C23H25F3N8O3
Molecular Weight
518.49
References & Citations
[1]WO 2014145909 A2.|[2]Yang WQ, Zhao WJ, Zhu LL, et al. XMD-17-51 Inhibits DCLK1 Kinase and Prevents Lung Cancer Progression. Front Pharmacol. 2021;12:603453.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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