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XMD-17-51 (TFA)

XMD-17-51 TFA is a pyrimido-diazepinone compound that is able to modulate protein kinases[1].

Product Specifications

CAS Number

2436579-93-8

UNSPSC

12352005

Target

AMPK; Bcr-Abl; ERK; Mps1; Polo-like Kinase (PLK) ; Trk Receptor

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton; Epigenetics; MAPK/ERK Pathway; Neuronal Signaling; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/xmd-17-51-tfa.html

Purity

99.46

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1N(C)C2=CN=C(NC3=CN(C4CCNCC4)N=C3)N=C2N(C)C5=CC=CC=C15.OC(C(F)(F)F)=O

Molecular Formula

C23H25F3N8O3

Molecular Weight

518.49

References & Citations

[1]WO 2014145909 A2.|[2]Yang WQ, Zhao WJ, Zhu LL, et al. XMD-17-51 Inhibits DCLK1 Kinase and Prevents Lung Cancer Progression. Front Pharmacol. 2021;12:603453.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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