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Otamixaban (hydrochloride)

Otamixaban (FXV673) is a potent, selective, rapid-acting, competitive, and reversible fXa inhibitor (Ki=0.5 nM) that effectively inhibits both free and prothrombinase-bound fXa[1].

Product Specifications

CAS Number

[409081-12-5]

Product Name Alternative

FXV673 (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Factor Xa

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/otamixaban-hydrochloride.html

Purity

98.50

Solubility

10 mM in DMSO

Smiles

N=C(N)C1=CC=CC(C[C@@H](C(OC)=O)[C@@H](C)NC(C2=CC=C(C3=CC=[N+]([O-])C=C3)C=C2)=O)=C1.Cl

Molecular Formula

C25H27ClN4O4

Molecular Weight

482.96

Precautions

H302, H315, H319, H335

References & Citations

[1]Eikelboom JW, Weitz JI.Otamixaban in acute coronary syndromes.Lancet. 2009 Sep 5;374 (9692) :762-4. Epub 2009 Aug 28.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Phase 3

Available Sizes

Curated Selection

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