Siglec-3/CD33, Mouse (HEK293, Fc)
Siglec-3/CD33, a sialic-acid-binding lectin, crucially mediates cell-cell interactions and immune cell quiescence. Preferring sialic acid on specific mucins, it forms homodimers, interacting with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation. CD33 also engages C1QA through its C-terminus, activating CD33 inhibitory motifs. Siglec-3/CD33 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Siglec-3/CD33 protein, expressed by HEK293 , with C-hFc labeled tag.
Product Specifications
Product Name Alternative
Siglec-3/CD33 Protein, Mouse (HEK293, Fc), Mouse, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/siglec-3-cd33-protein-mouse-hek293-fc.html
Purity
94.00
Molecular Formula
12489 (Gene_ID) Q63994-1 (Q17-E240) (Accession)
Molecular Weight
55-60 kDa
Shipping Conditions
Dry ice
Storage Conditions
Stored at -80°C for 1 year
Scientific Category
Recombinant Proteins
Available Sizes
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