Phospho-c-Cbl (Tyr700) Rabbit Antibody APC Conjugate

<strong>Phospho-c-Cbl (Tyr700) Rabbit Antibody APC Conjugate</strong>_x000D_ <strong>Catalog number:</strong> B2018415_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 Tests_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8 °C_x000D_ <strong>Keywords:</strong> E3 ubiquitin-protein ligase CBL, Casitas B-lineage lymphoma proto-oncogene, Proto-oncogene c-Cbl, RING finger protein 55, RING-type E3 ubiquitin transferase, Signal transduction protein CBL, CBL2, RNF55_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Duan L, Raja SM, Chen G, Virmani S, Williams SH, Clubb RJ, Mukhopadhyay C, Rainey MA, Ying G, Dimri M, Chen J, Reddi AL, Naramura M, Band V, Band H. Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration J Biol Chem. 2011 Jan 7;286(1):620-33._x000D_ 2: Mitsushima M, Ueda K, Kioka N. Vinexin beta regulates the phosphorylation of epidermal growth factor receptor on the cell surface Genes Cells. 2006 Sep;11(9):971-82._x000D_ 3: Meyer RD, Sacks DB, Rahimi N. IQGAP1-dependent signaling pathway regulates endothelial cell proliferation and angiogenesis PLoS One. 2008;3(12):e3848._x000D_ 4: Kadera BE, Toste PA, Wu N, Li L, Nguyen AH, Dawson DW, Donahue TR. Low expression of the E3 ubiquitin ligase CBL confers chemoresistance in human pancreatic cancer and is targeted by epidermal growth factor receptor inhibition Clin Cancer Res. 2015 Jan 1;21(1):157-65._x000D_ 5: Ohno A, Ochi A, Maita N, Ueji T, Bando A, Nakao R, Hirasaka K, Abe T, Teshima-Kondo S, Nemoto H, Okumura Y, Higashibata A, Yano S, Tochio H, Nikawa T. Structural analysis of the TKB domain of ubiquitin ligase Cbl-b complexed with its small inhibitory peptide, Cblin Arch Biochem Biophys. 2016 Mar 15;594:1-7._x000D_ 6: Samet JM, Dewar BJ, Wu W, Graves LM. Mechanisms of Zn(2+)-induced signal initiation through the epidermal growth factor receptor Toxicol Appl Pharmacol. 2003 Aug 15;191(1):86-93._x000D_ 7: Artemenko Y, Gagnon A, Sorisky A. Catalytically inactive SHIP2 inhibits proliferation by attenuating PDGF signaling in 3T3-L1 preadipocytes J Cell Physiol. 2009 Jan;218(1):228-36._x000D_ 8: Yoneda K, Demitsu T, Nakai K, Moriue T, Ogawa W, Igarashi J, Kosaka H, Kubota Y. Activation of vascular endothelial growth factor receptor 2 in a cellular model of loricrin keratoderma J Biol Chem. 2010 May 21;285(21):16184-94._x000D_ 9: Schroeder B, Srivatsan S, Shaw A, Billadeau D, McNiven MA. CIN85 phosphorylation is essential for EGFR ubiquitination and sorting into multivesicular bodies Mol Biol Cell. 2012 Sep;23(18):3602-11._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/15828871">10: Row PE, Clague MJ, Urbé S. Growth factors induce differential phosphorylation profiles of the Hrs-STAM complex: a common node in signalling networks with signal-specific properties Biochem J. 2005 Aug 1;389(Pt 3):629-36. </a>_x000D_ _x000D_ <strong>Products Related to Phospho-c-Cbl (Tyr700) Rabbit Antibody APC Conjugate can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>