2-Epitripdiolide

2-Epitripdiolide is a diterpenoid compound derived from Tripterygium hypoglaucum with significant antitumor activity. Its IC50 values against A549, KB, KBvin, and MDA-MB-231 cells are 1.34, 0.4, 4.4, and 1.2 nM, respectively[1].

Product Specifications

CAS Number

[74409-90-8]

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/2-epitripdiolide.html

Smiles

C[C@@]12[C@@]34[C@]5([C@@H]([C@@]6([C@](O6)([H])[C@]3([H])O4)C(C)C)O)[C@@](C[C@@]1([H])C7=C(C(OC7)=O)[C@@H](C2)O)([H])O5

Molecular Formula

C20H24O7

Molecular Weight

376.40

References & Citations

[1]Li X L, et al. Diterpenoids from the stems of Tripterygium hypoglaucum (Celastraceae) and cytotoxic evaluation[J]. Phytochemistry Letters, 2015, 12: 84-89.