SLU-PP-1072

SLU-PP-1072 is a dual ERRα/γ inverse agonist, used in Prostate cancer (PCa) research. SLU-PP-1072 disrupts PCa cell metabolism, and induces apoptosis via dysregulating cell cycle[1].

Product Specifications

CAS Number

[2285432-57-5]

UNSPSC

12352005

Target

Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/slu-pp-1072.html

Purity

98.24

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(C2=CC=C(O)C=C2)O1)NC3=CC4=C(N=CS4)C=C3

Molecular Formula

C18H12N2O3S

Molecular Weight

336.36

References & Citations

[1]Schoepke E, et al. A Selective ERRα/γ Inverse Agonist, SLU-PP-1072, Inhibits the Warburg Effect and Induces Apoptosis in Prostate Cancer Cells. ACS Chem Biol. 2020 Sep 18;15 (9) :2338-2345.