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Telacebec

Telacebec (Q203) is a midazopyridine amide compound. Telacebec is active against Mycobacterium tuberculosis H37Rv with an MIC50 of 2.7 nM in culture broth medium.

Product Specifications

CAS Number

[1334719-95-7]

Product Name Alternative

Q203; IAP6

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/telacebec.html

Purity

99.45

Solubility

DMSO : 20 mg/mL (ultrasonic)

Smiles

O=C(C1=C(CC)N=C2C=CC(Cl)=CN21)NCC3=CC=C(N4CCC(C5=CC=C(OC(F)(F)F)C=C5)CC4)C=C3

Molecular Formula

C29H28ClF3N4O2

Molecular Weight

557.01

Precautions

H315, H319, H335

References & Citations

[1]Pethe K, et al. Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis. Nat Med. 2013 Sep;19 (9) :1157-60.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Curated Selection

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