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FFAR1/FFAR4 agonist-1

FFAR1/FFAR4 agonist-1 (compound 83) is a FFAR1/FFAR4 agonist with the EC50 of 1 nM A and 4nM for FFAR1 and FFAR4, respectively. FFAR1/FFAR4 agonist-1 can be used for study of glycemic control[1].

Product Specifications

CAS Number

2839486-16-5

UNSPSC

12352005

Target

Free Fatty Acid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ffar1-ffar4-agonist-1.html

Smiles

O=C1N(CCC1)C2=CC(OCC3=NC(NCCC4=CC(Cl)=CC=C4Cl)=NC(N)=N3)=CC(C)=C2

Molecular Formula

C23H24Cl2N6O2

Molecular Weight

487.38

References & Citations

[1]Lückmann M, et al. Optimization of First-in-Class Dual-Acting FFAR1/FFAR4 Allosteric Modulators with Novel Mode of Action. ACS Med Chem Lett. 2022;13 (12) :1839-1847. Published 2022 Nov 2.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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