Alloferon 1

Alloferon 1 is an antiviral and antitumoral peptide. Alloferon 1 stimulates natural cytotoxicity of human peripheral blood lymphocytes. Alloferon 1 also induces IFN synthesis, and enhances antiviral and antitumor resistance in mice. Alloferon 1 also shows anti-inflammatory activity in λ-carrageenan-induced paw edema model. Alloferon 1 can be isolated from the blood of the blow fly Calliphora vicina (Diptera) [1][2][3].

Product Specifications

CAS Number

[347884-61-1]

UNSPSC

12352209

Target

Others

Type

Peptides

Related Pathways

Others

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/alloferon-1.html

Purity

99.97

Solubility

DMSO : 4.55 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

N[C@@H](CC1=CN=CN1)C(NCC(N[C@@H](C(C)C)C(N[C@@H](CO)C(NCC(N[C@@H](CC2=CN=CN2)C(NCC(N[C@@H](CCC(N)=O)C(N[C@H](C(NCC(N[C@@H](C(C)C)C(N[C@H](C(NCC(O)=O)=O)CC3=CN=CN3)=O)=O)=O)CC4=CN=CN4)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C52H76N22O16

Molecular Weight

1265.30

References & Citations

[1]Chernysh S, et al. Antiviral and antitumor peptides from insects. Proc Natl Acad Sci U S A. 2002 Oct 1;99 (20) :12628-32.|[2]Zhang X, et al. Alloferon-1 ameliorates acute inflammatory responses in λ-carrageenan-induced paw edema in mice. Sci Rep. 2022 Oct 6;12 (1) :16689.