(±) -BAK2-66

(±) -BAK2-66 is a selectivity dopamine D3 receptor antagonist with theKi values of 1nM and 960 nM for D3R and D2R, respectively. (±) -BAK2-66 can be used for study in animal models of addiction[1].

Product Specifications

CAS Number

1301178-83-5

UNSPSC

12352005

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/racemic-bak2-66.html

Smiles

O=C(NCCC(CN1CCN(CC1)C2=CC=CC(Cl)=C2Cl)F)C3=CC4=CC=CC=C4O3

Molecular Formula

C23H24Cl2FN3O2

Molecular Weight

464.36

References & Citations

[1]Kumar V, et al. Chiral Resolution and Serendipitous Fluorination Reaction for the Selective Dopamine D3 Receptor Antagonist BAK2-66. ACS Med Chem Lett. 2014;5 (6) :647-651. Published 2014 Mar 24.