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Biotin anti Human IgM Antibody (μ-chain specific)

<strong>Biotin anti Human IgM Antibody</strong>_x000D_ <table width="492">_x000D_ <tbody>_x000D_ <tr>_x000D_ <td>Catalog number:</td>_x000D_ <td>A2010046</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Lot number:</td>_x000D_ <td>Batch Dependent</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Expiration date:</td>_x000D_ <td>Batch Dependent</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Package Size:</td>_x000D_ <td>10 mg</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Other names:</td>_x000D_ <td>Biotinylated anti Human IgM Antibody,  biotin anti IgM, biotinylated anti IgM, anti-human IgM biotinylated.</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Supplied as:</td>_x000D_ <td>Solution</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Concentration:</td>_x000D_ <td>5.0 mg/mL</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Clonality:</td>_x000D_ <td>Polyclonal</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Host:</td>_x000D_ <td>Goat</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Specificity:</td>_x000D_ <td>Human IgM (μ-chain specific)</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Cross Reactivity:</td>_x000D_ <td>No cross-reaction with human IgG</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Purity</td>_x000D_ <td>&gt; 95% (SDS-PAGE)</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Immunogen</td>_x000D_ <td>Human IgM antibodies</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Preservative:</td>_x000D_ <td>none</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Storage:</td>_x000D_ <td>2-8°C (short term), -20°C (long term). Avoid repeated freeze-thaw.</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Buffer:</td>_x000D_ <td width="325">10 mM Sodium phosphate pH 7.0 + 150 mM NaCl</td>_x000D_ </tr>_x000D_ </tbody>_x000D_ </table>_x000D_ <strong>References</strong>_x000D_ <ul>_x000D_ <li class="title">Joseph LF, Ezhevsky S, Scott DW. Lymphoma models for B-cell activation and tolerance: anti-immunoglobulin M treatment induces growth arrest by preventing the formation of an active kinase complex which phosphorylates retinoblastoma gene product in G1. <span class="jrnl" title="Cell growth &amp; differentiation : the molecular biology journal of the American Association for Cancer Research">Cell Growth Differ</span>. 1995 Jan;6(1):51-7.</li>_x000D_ <li class="title">Komada Y, Zhang XL, Zhou YW, Tanaka S, Higashigawa M, Ido M, Sakurai M. Apoptotic cell death induced by <b>anti-IgM</b> antibody and phorbol esters is inhibited by interleukin-4 in human B lymphoma cell line MBC-1. <span class="jrnl" title="Cellular immunology">Cell Immunol</span>. 1994 Dec;159(2):280-93.</li>_x000D_ <li class="title">Laskin CA, Chuma A, Angelov L, Neil G, Levy GA, Mason N, Soloninka C, Cole E. Sera from habitual aborters induce monocyte procoagulant activity: a lymphocyte-dependent event. <span class="jrnl" title="Clinical immunology and immunopathology">Clin Immunol Immunopathol</span>. 1994 Nov;73(2):235-44.</li>_x000D_ <li class="supp">_x000D_ <p class="title">Abed NS, Chace JH, Cowdery JS. T cell-independent and T cell-dependent B cell activation increases IFN-gamma R expression and renders B cells sensitive to IFN-gamma-mediated inhibition. <span class="jrnl" title="Journal of immunology (Baltimore, Md. : 1950)">J Immunol</span>. 1994 Oct 15;153(8):3369-77.</p>_x000D_ </li>_x000D_ <li class="supp">_x000D_ <p class="title">Sumimoto S, Heike T, Kanazashi S, Shintaku N, Jung EY, Hata D, Katamura K, Mayumi M. Involvement of LFA-1/intracellular adhesion molecule-1-dependent cell adhesion in CD40-mediated inhibition of human B lymphoma cell death induced by surface IgM crosslinking. <span class="jrnl" title="Journal of immunology (Baltimore, Md. : 1950)">J Immunol</span>. 1994 Sep 15;153(6):2488-96.</p>_x000D_ </li>_x000D_ <li class="supp">_x000D_ <p class="title">Proulx C, Filion M, Goldman M, Bradley A, Devine D, Décary F, Chartrand P. Analysis of immunoglobulin class, IgG subclass and titre of HPA-1a antibodies in alloimmunized mothers giving birth to babies with or without neonatal alloimmune thrombocytopenia. <span class="jrnl" title="British journal of haematology">Br J Haematol</span>. 1994 Aug;87(4):813-7.</p>_x000D_ </li>_x000D_ <li class="title">Sindic CJ, Monteyne P, Laterre EC. Occurrence of oligoclonal IgM bands in the cerebrospinal fluid of neurological patients: an immunoaffinity-mediated capillary blot study. <a href="https://www.ncbi.nlm.nih.gov/pubmed/7964874"><span class="jrnl" title="Journal of the neurological sciences">J Neurol Sci</span>. 1994 Jul;</a>124(2):215-9.</li>_x000D_ </ul>_x000D_ &nbsp;_x000D_ _x000D_ <strong>Related Products</strong>_x000D_ _x000D_ https://moleculardepot.com/product/anti-human-igm-antibody-polyclonal/_x000D_ _x000D_ https://moleculardepot.com/product/anti-igm-antibody-monoclonal/_x000D_ _x000D_ &nbsp;

Product Specifications

CAS Number

9007-83-4

Short Description

Catalog #: A2010046 (10 mg)

Weight

0.15

Length

2

Width

0.5

Height

0.5

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