Lyn-IN-1
Lyn-IN-1 (Bafetinib analog) is a Lyn kinase inhibitor for the study of thrombocytopenia[1].
Product Specifications
CAS Number
[887650-05-7]
Product Name Alternative
Bafetinib analog
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bcr-Abl
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Lyn-IN-1.html
Purity
98.93
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=C(C)C(NC2=NC=C(C3=CN=CN=C3)C=N2)=C1)C4=CC=C(CN5C[C@@H](N(C)C)CC5)C(C(F)(F)F)=C4
Molecular Formula
C30H31F3N8O
Molecular Weight
576.62
Precautions
H302, H315, H319, H335
References & Citations
[1]Nan W, et al. Antagonism of abcg4, lyn kinase, and c-cbl e3 ligase to increase platelet count as therapy for thrombocytopenia. WO2014169128A1. The Trustees Of Columbia University. 2014
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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