Sulfo-SPP
Sulfo-SPP is a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.
Product Specifications
CAS Number
452072-27-4
UNSPSC
12352203
Hazard Statement
H302-H315-H319-H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sulfo-spp.html
Purity
97.14
Solubility
10 mM in DMSO
Smiles
CC(SSC1=NC=CC=C1)CCC(ON2C(C(S(=O)(O)=O)CC2=O)=O)=O
Molecular Formula
C14H16N2O7S3
Molecular Weight
420.48
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Ravi V. J. Chari, et al. Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents. US6441163B1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Disulfide Cleavable Linker
Available Sizes
Frequently Asked Questions
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