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2-TEDC

2-TEDC is a potent inhibitor of 5-, 12-, and 15-lipoxygenase with IC50 values of 0.09 μM, 0.013 μM and 0.5 μM, respectively. 2-TEDC can be used for the research of atheroscrelosi[1].

Product Specifications

CAS Number

[132465-10-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Lipoxygenase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/2-tedc.html

Concentration

10mM

Purity

99.58

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(OCCC1=CC=CS1)/C(C#N)=C/C2=CC=C(O)C(O)=C2

Molecular Formula

C16H13NO4S

Molecular Weight

315.34

Precautions

H302, H315, H319, H335

References & Citations

[1]H Cho, et al. Novel caffeic acid derivatives: extremely potent inhibitors of 12-lipoxygenase. J Med Chem. 1991 Apr;34 (4) :1503-5.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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