Patiromer
Patiromer is an orally active, selective and non-absorbable intestinal potassium (K+) polymer binder that reversibly binds potassium ions in exchange for calcium (Ca2+) . Patiromer can rapidly and continuously reduce serum potassium levels, maintain a normal blood potassium state, and reduce serum aldosterone levels. Patiromer also increases fecal potassium excretion. Patiromer is mainly used in the study of hyperkalemia associated with diseases such as chronic kidney disease, diabetes, and heart failure, and is particularly suitable for improving renin-angiotensin-aldosterone system inhibitor (RAASi) therapy[1][2][3].
Product Specifications
CAS Number
1208912-84-8
UNSPSC
12352211
Target
Interleukin Related; JAK; STAT
Type
Reference compound
Related Pathways
Epigenetics; Immunology/Inflammation; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/patiromer.html
Purity
95.0
Solubility
H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CCC(C([O-])=O)(F)CC(C1=CC=CC=C1)CC(CCCCC(C)CC)C.CC(CC)C.[Ca+2].[p].[p].[n].[m].[n].[1/2]
Molecular Formula
(C10H10.C8H14.C3H3FO2.1/2Ca) x
References & Citations
Shipping Conditions
Isolate blue ice and the product with bubble pack to avoid direct contact
Storage Conditions
Store at 4°C, do not freeze
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
IL-15; IL-2; IL-4; IL-7; JAK3; STAT3; STAT5; STAT6
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Tauro 6-Ethylchenodeoxycholic Acid Sodium SaltREPLACES E917458.
Human IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker) (IGHM/1623), CF740 conjugate, 0.1mg/mL
Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), 0.2mg/mL
