Eupatorin
Eupatorin, a naturally occurring flavone, arrests cells at the G2-M phase of the cell cycle and induces apoptotic cell death involving activation of multiple caspases, mitochondrial release of cytochrome c and poly (ADP-ribose) polymerase cleavage[1].
Product Specifications
CAS Number
[855-96-9]
UNSPSC
12352005
Hazard Statement
H301
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/eupatorin.html
Purity
99.97
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C1C=C(C2=CC=C(OC)C(O)=C2)OC3=CC(OC)=C(OC)C(O)=C13
Molecular Formula
C18H16O7
Molecular Weight
344.32
Precautions
H301
References & Citations
[1]Estévez S, et al. Eupatorin-induced cell death in human leukemia cells is dependent on caspases and activates the mitogen-activated protein kinase pathway. PLoS One. 2014 Nov 12;9 (11) :e112536.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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