(R) -Lisofylline
(R) -Lisofylline ((R) -Lisophylline) is a (R) -enantiomer of the metabolite of Pentoxifylline with anti-inflammatory properties. (R) -Lisofylline is a lysophosphatidic acid acyltransferase inhibitor with an IC50 of 0.6 μM and interrupts IL-12 signaling-mediated STAT4 activation. (R) -Lisofylline has the potential for type 1 diabetes, autoimmune disorders research[1][2].
Product Specifications
CAS Number
100324-81-0
Product Name Alternative
(R) -Lisophylline
UNSPSC
12352005
Target
STAT
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/r-lisofylline.html
Purity
99.99
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1CCCC[C@H](O)C)N(C)C2=C(N(C)C=N2)C1=O
Molecular Formula
C13H20N4O3
Molecular Weight
280.32
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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