CIGB-300
CIGB-300 (P15-Tat) is an anti-casein kinase 2 (CK2) peptide that exhibits anticancer properties by interfering with the phosphorylation of protein kinase CK2. CIGB-300 induces apoptosis in multiple tumor cell lines and can be used in cancer research[1].
Product Specifications
CAS Number
1072877-99-6
Product Name Alternative
P15-Tat
UNSPSC
12352209
Target
Apoptosis; Casein Kinase
Type
Peptides
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cigb-300.html
Smiles
O=C(N[C@H](C(N[C@H](C(N1[C@](CCC1)([H])C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@@](C(N[C@@H](CSSC[C@@H](C(N2)=O)NC(CCNC([C@H](CCC(N)=O)NC([C@H]3N(CCC3)C([C@H]4N(CCC4)C([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@@H](NC(CN)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(O)=O)=O)([H])[C@H](O)C)=O)=O)CC(C)C)=O)CC5=CN=CN5)=O)CCCNC(N)=N)=O)=O)CO)=O)CCSC)[C@@H]2CC6=CNC7=CC=CC=C67
Molecular Formula
C127H215N53O30S3
Molecular Weight
3060.60
References & Citations
[1]Perea S E, et al. CIGB-300, a novel proapoptotic peptide that impairs the CK2 phosphorylation and exhibits anticancer properties both in vitro and in vivo[J]. Molecular and cellular biochemistry, 2008, 316: 163-167.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
Phase 3
Frequently Asked Questions
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