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DDP-38003 (dihydrochloride)

Product Specifications

UNSPSC Description

DDP-38003 dihydrochloride is an novel, orally available inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) with an IC50 of 84 nM[1].

Target Antigen

Histone Demethylase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/DDP-38003-dihydrochloride.html

Purity

98.22

Solubility

DMSO : ≥ 29 mg/mL

Smiles

[H]Cl.O=C(NC1=CC=C([C@@H]2C[C@H]2N)C=C1)C(C=C3)=CC=C3N4CCN(C)CC4.[H]Cl

Molecular Weight

423.38

References & Citations

[1]Vianello P, et al. Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent. J Med Chem. 2016 Feb 25;59(4):1501-17.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-19612A/DDP-38003-dihydrochloride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-19612A/DDP-38003-dihydrochloride-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1831167-98-6

Available Sizes

Curated Selection

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