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Pomalidomide-PEG4-C2-NH2 (hydrochloride)

Pomalidomide-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in the synthesis of PROTACs..

Product Specifications

CAS Number

2357105-92-9

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pomalidomide-peg4-c2-nh2-hydrochloride.html

Purity

98.18

Solubility

DMSO : 220 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCOCCOCCN)=O.Cl

Molecular Formula

C23H33ClN4O8

Molecular Weight

528.98

Precautions

H302, H315, H319, H335

References & Citations

[1]Jian Jin, et al. Compositions and methods for treating ezh2-mediated cancer. WO2018081530A1.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Available Sizes

Frequently Asked Questions

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