Pomalidomide-PEG4-C2-NH2 (hydrochloride)
Pomalidomide-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in the synthesis of PROTACs..
Product Specifications
CAS Number
[2357105-92-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-peg4-c2-nh2-hydrochloride.html
Purity
98.18
Solubility
DMSO : 220 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCOCCOCCN)=O.Cl
Molecular Formula
C23H33ClN4O8
Molecular Weight
528.98
Precautions
H302, H315, H319, H335
References & Citations
[1]Jian Jin, et al. Compositions and methods for treating ezh2-mediated cancer. WO2018081530A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
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