BI-6901
Product Specifications
Product Name Alternative
TC-1734; ACD3480
UNSPSC Description
BI 6901 is a potent, selective CCR10 antagonist (pIC50=9.0). BI 6901 shows high selectivity over other GPCRs, including a number of other chemokine receptors. BI 6901 is efficacious in the murine DNFB model of contact hypersensitivity and can be used for inflammation research[1].
Target Antigen
CCR
Type
Reference compound
Related Pathways
GPCR/G Protein;Immunology/Inflammation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bi-6901.html
Purity
99.94
Solubility
DMSO : 160 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=CC2=C1C=CN2)(N[C@@H](C(N3CCC(C)CC3)=O)CCN4C(C#N)=CC=C4)=O
Molecular Weight
453.56
References & Citations
[1]Asitha Abeywardane, et al. N-Arylsulfonyl-α-amino carboxamides are potent and selective inhibitors of the chemokine receptor CCR10 that show efficacy in the murine DNFB model of contact hypersensitivity. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5277-5283.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116835/BI-6901-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116835/BI-6901-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2040401-92-9
Available Sizes
Curated Selection
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