PTGS2 antibody
Product Specifications
Background
COX2 (Prostaglandin G/H synthase 2; PTGS2) mediates the formation of prostaglandins from arachidonate. Its subunit structure is homodimer. The fully N-glycosylated PTGS2 is 72–74 kDa and the aglycosylated is 66 kDa (PMID:19656660) . It also expresses a band of 39 kDa after unspecific cleavage (PMID:17509125) . The 50 kDa band of fragmented PTGS2 has also previously been detected in AD brains (PMID:14724276) .
Synonyms
Prostaglandin G/H synthase 2|Cyclooxygenase-2 (COX-2) |PHS II|Prostaglandin H2 synthase 2 (PGH synthase 2, PGHS-2) |Prostaglandin-endoperoxide synthase 2|PTGS2|COX2
Gene ID
5743
UniProt
P35354
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
Target
PTGS2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Cancer, Cardiovascular, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50 kDa, 80 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
104-209aa
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