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PTGS2 antibody

Product Specifications

Background

COX2 (Prostaglandin G/H synthase 2; PTGS2) mediates the formation of prostaglandins from arachidonate. Its subunit structure is homodimer. The fully N-glycosylated PTGS2 is 72–74 kDa and the aglycosylated is 66 kDa (PMID:19656660) . It also expresses a band of 39 kDa after unspecific cleavage (PMID:17509125) . The 50 kDa band of fragmented PTGS2 has also previously been detected in AD brains (PMID:14724276) .

Synonyms

Prostaglandin G/H synthase 2|Cyclooxygenase-2 (COX-2) |PHS II|Prostaglandin H2 synthase 2 (PGH synthase 2, PGHS-2) |Prostaglandin-endoperoxide synthase 2|PTGS2|COX2

Gene ID

5743

UniProt

P35354

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Target

PTGS2

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Cancer, Cardiovascular, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

50 kDa, 80 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

Immunogen Sequence

104-209aa

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