L-659837
Product Specifications
UNSPSC Description
L-659837 is a NK2 receptor antagonist, and can antagonize GR 64349 (HY-P1278)-induced contraction. L-659837 can be used for study of urinary bladder disorders[1].
Target Antigen
Neurokinin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/l-659837.html
Smiles
CC(C)C[C@@H](C(N[C@@H](CCSC)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC1=CNC2=CC=CC=C21)C(N[C@H]3CC4=CC=CC=C4)=O)=O)=O)=O)[N@]5CC[C@H](C5=O)NC3=O
Molecular Weight
788.96
References & Citations
[1]Palea S, et al. Pharmacological characterization of tachykinin NK2 receptors on isolated human urinary bladder, prostatic urethra and prostate. J Pharmacol Exp Ther. 1996;277(2):700-705.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P2436/L-659837-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P2436/
Clinical Information
No Development Reported
CAS Number
125989-10-8
Curated Selection
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