CDC25B-IN-1
Product Specifications
UNSPSC Description
CDC25B-IN-1 (compound 4a) is a potent inhibitor of cell division cycle 25B (CDC25B) phosphatase, with a Ki of 8.5 μM. CDC25B-IN-1 potently inhibits cell proliferation and colony formation, causes an increase of the G2/M phase[1].
Target Antigen
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdc25b-in-1.html
Purity
98.09
Solubility
DMSO : 100 mg/mL (ultrasonic)|Ethanol : 50 mg/mL (ultrasonic)
Smiles
COC1=CC2=CC=CC=C2C(NC3=CC=CC(C(OCC)=O)=C3)=C1
Molecular Weight
321.37
References & Citations
[1]Cerchia C, et al. Discovery of Novel Naphthylphenylketone and Naphthylphenylamine Derivatives as Cell Division Cycle 25B (CDC25B) Phosphatase Inhibitors: Design, Synthesis, Inhibition Mechanism, and in Vitro Efficacy against Melanoma Cell Lines. J Med Chem. 2019 Aug 8;62(15):7089-7110.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-126246/CDC25B-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-126246/CDC25B-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2374831-10-2
Available Sizes
Curated Selection
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