Linperlisib

Linperlisib (YY-20394) is a potent, orally bioavailable and selective inhibitor of PI3Kδ extracted from patent WO 2015055071 A1, compound 10; has an IC50 of 6.4 nM[1].

Product Specifications

CAS Number

[1702816-75-8]

Product Name Alternative

YY-20394

UNSPSC

12352005

Target

PI3K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/PI3K_delta_-IN-2.html

Purity

98.91

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CS(=O)(NC1=CC(C2=C3C=C(F)C=C(CN4CCC(C(C)(O)C)CC4)C3=NC(N5CCOCC5)=N2)=CN=C1OC)=O

Molecular Formula

C28H37FN6O5S

Molecular Weight

588.69

References & Citations

[1]WO 2015055071 A1

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 4

Isoform

PI3Kδ

Available Sizes

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