6-O-Isobutyrylbritannilactone
6-O-Isobutyrylbritannilactone is a natural melanogenesis inhibitor. 6-O-Isobutyrylbritannilactone, a sesquiterpene, can be isolated from the flowers of Inula britannica. 6-O-Isobutyrylbritannilactone inhibits IBMX -induced melanin production in B16F10 cells. 6-O-Isobutyrylbritannilactone also regulates ERK, PI3K/AKT, and CREB, shows antimelanogenic activity in zebrafish embryos models[1].
Product Specifications
CAS Number
1259933-02-2
UNSPSC
12352005
Hazard Statement
H302
Target
Akt; Epigenetic Reader Domain; ERK; PI3K
Type
Natural Products
Related Pathways
Epigenetics; MAPK/ERK Pathway; PI3K/Akt/mTOR; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/6-o-isobutyrylbritannilactone.html
Solubility
10 mM in DMSO
Smiles
CC(C)C(O[C@H]1[C@@]2([H])[C@@](OC(C2=C)=O)([H])CC(C)=C1[C@@H](C)CCCO)=O
Molecular Formula
C19H28O5
Molecular Weight
336.42
Precautions
P264-P270-P330-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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