Neuropeptide W-23 (human)
Product Specifications
UNSPSC Description
Neuropeptide W-23 (human) (NPW-23), the active form of Neuropeptide W, is an endogenous agonist of NPBW1 (GPR7) and NPBW2 (GPR8)[1].
Target Antigen
Neuropeptide B/W Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/neuropeptide-w-23-human.html
Purity
99.84
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CCCCN)C(N[C@@H](CC2=CNC=N2)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CO)C(N3[C@@H](CCC3)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC4=CC=C(C=C4)O)C(N[C@@H](CC5=CNC=N5)C(N[C@@H]([C@H](O)C)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](C)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCSC)C(NCC(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC6=CNC7=CC=CC=C67)N
Molecular Weight
2584.01
References & Citations
[1]Ji L, et al. Modulation of CaV1.2 calcium channel by neuropeptide W regulates vascular myogenic tone via G protein-coupled receptor 7. J Hypertens. 2015 Dec;33(12):2431-42.|[2]Pate AT, et al. Neuropeptide W increases mean arterial pressure as a result of behavioral arousal. Am J Physiol Regul Integr Comp Physiol. 2013 Oct 1;305(7):R804-10.|[3]Naso T, et al. Central neuropeptide W has anorexigenic effect in rats. J Anim Physiol Anim Nutr (Berl). 2014 Apr;98(2):228-34.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P1035/Neuropeptide-W-23-human-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P1035/Neuropeptide-W-23-human-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
383415-79-0
Available Sizes
Curated Selection
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