CS-722

CS-722 is a centrally acting muscle relaxant, and has a muscle relaxant activity and depressant effectson the spinal reflex[1]. CS-722 inhibits spontaneous inhibitory postsynaptic currents and excitatory postsynaptic currents in hippocampal cultures probably by an inhibition of both sodium and calcium currents[1][2].

Product Specifications

CAS Number

[144886-17-9]

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cs-722.html

Smiles

ClC1=C(C2=CC=CC=C2)ON(C[C@H](O)CN3CCOCC3)C1=O.Cl

Molecular Formula

C16H20Cl2N2O4

Molecular Weight

375.25

References & Citations

[1]Marszalec W, et al. The effects of the muscle relaxant, CS-722, on synaptic activity of cultured neurones. Br J Pharmacol. 1996 Sep;119 (1) :126-32. |[2]Tanabe M, et al. Preferential enhancement of inhibitory synaptic transmission by CS-722 in the ventral horn neurons of neonatal rat spinal cord. Eur J Pharmacol. 1996 Oct 17;313 (3) :187-9.