Prolactin-Releasing Peptide (12-31), rat

Prolactin-Releasing Peptide (12-31), rat is a fragment of the prolactin releasing peptide (PrRP) . Prolactin-Releasing Peptide (12-31), rat shows high affinity for GPR10 receptors. Prolactin-Releasing Peptide (12-31), stimulates calcium mobilization in CHOK1 cells transfected with the PrRP receptor[1][2].

Product Specifications

CAS Number

[222988-10-5]

UNSPSC

12352209

Target

GnRH Receptor; Orphan Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/prolactin-releasing-peptide-12-31-rat.html

Purity

99.96

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

OC(C=C1)=CC=C1C[C@@H](C(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@@H](NC([C@H](C)NC([C@H]4N(CCC4)C([C@H](CC(N)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CC(O)=O)NC([C@H]5N(CCC5)C([C@@H](N)[C@H](O)C)=O)=O)=O)=O)=O)=O)=O)CC6=CNC7=CC=CC=C67)=O

Molecular Formula

C104H158N32O26

Molecular Weight

2272.57

References & Citations

[1]Roland BL, et al. Anatomical distribution of prolactin-releasing peptide and its receptor suggests additional functions in the central nervous system and periphery. Endocrinology. 1999 Dec;140 (12) :5736-45.|[2]Langmead CJ, et al. Characterization of the binding of [ (125) I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor. Br J Pharmacol. 2000 Oct;131 (4) :683-8.