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Guanylin (human) (TFA)

Guanylin (human) TFA, a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin (human) TFA is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism[1][2].

Product Specifications

UNSPSC

12352209

Target

Endogenous Metabolite; Guanylate Cyclase

Type

Peptides

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/guanylin-human-tfa.html

Purity

98.5

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

O=C([C@@H](NC([C@@]1([H])NC([C@](NC([C@@H](NC([C@H](CSSC[C@](C(N[C@@](C(NCC(N[C@@H](CSSC1)C(O)=O)=O)=O)([H])[C@H](O)C)=O)([H])NC([C@@H](NC([C@@H](NC2=O)C)=O)C)=O)NC([C@H]([C@H](O)C)NC(CNC([C@@H]3CCCN3)=O)=O)=O)=O)CCC(O)=O)=O)([H])[C@@H](C)CC)=O)=O)C)N[C@H]2CC4=CC=C(C=C4)O.OC(C(F)(F)F)=O

Molecular Formula

C60H88F3N15O23S4

Molecular Weight

1572.68

References & Citations

[1]M G Currie, et al. Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc Natl Acad Sci U S A. 1992 Feb 1;89 (3) :947-51.|[2]J Bełtowski. Guanylin and related peptides. J Physiol Pharmacol. 2001 Sep;52 (3) :351-75.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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