Guanylin (human) (TFA)
Guanylin (human) TFA, a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin (human) TFA is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism[1][2].
Product Specifications
UNSPSC
12352209
Target
Endogenous Metabolite; Guanylate Cyclase
Type
Peptides
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/guanylin-human-tfa.html
Purity
98.5
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL
Smiles
O=C([C@@H](NC([C@@]1([H])NC([C@](NC([C@@H](NC([C@H](CSSC[C@](C(N[C@@](C(NCC(N[C@@H](CSSC1)C(O)=O)=O)=O)([H])[C@H](O)C)=O)([H])NC([C@@H](NC([C@@H](NC2=O)C)=O)C)=O)NC([C@H]([C@H](O)C)NC(CNC([C@@H]3CCCN3)=O)=O)=O)=O)CCC(O)=O)=O)([H])[C@@H](C)CC)=O)=O)C)N[C@H]2CC4=CC=C(C=C4)O.OC(C(F)(F)F)=O
Molecular Formula
C60H88F3N15O23S4
Molecular Weight
1572.68
References & Citations
[1]M G Currie, et al. Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc Natl Acad Sci U S A. 1992 Feb 1;89 (3) :947-51.|[2]J Bełtowski. Guanylin and related peptides. J Physiol Pharmacol. 2001 Sep;52 (3) :351-75.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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