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Biotin-PEG4-SS-azide

Biotin-PEG4-SS-azide is a cleavable, biotin-labeled, ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Biotin-PEG4-SS-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

UNSPSC

12352203

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/biotin-peg4-ss-azide.html

Solubility

10 mM in DMSO

Smiles

O=C(NCCOCCOCCOCCOCCC(NCCSSCCC(NCCCN=[N+]=[N-])=O)=O)CCCC[C@H]1SC[C@@]([C@@]1([H])N2)([H])NC2=O

Molecular Formula

C29H52N8O8S3

Molecular Weight

736.97

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Cleavable Linker; Disulfide Cleavable Linker

Available Sizes

Frequently Asked Questions

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