Phospho-c-Cbl (Tyr774) Rabbit Antibody APC Conjugate

<strong>Phospho-c-Cbl (Tyr774) Rabbit Antibody APC Conjugate </strong>_x000D_ <strong>Catalog number:</strong> B2018313_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 Tests_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8 °C_x000D_ <strong>Keywords:</strong> E3 ubiquitin-protein ligase CBL, Casitas B-lineage lymphoma proto-oncogene, Proto-oncogene c-Cbl, RING finger protein 55, RING-type E3 ubiquitin transferase, Signal transduction protein CBL, CBL2, RNF55_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Wybenga-Groot LE, McGlade CJ. Sleuthing biochemical evidence to elucidate unassigned electron density in a CBL-SLAP2 crystal complex Acta Crystallogr F Struct Biol Commun. 2021 Feb 1;77(Pt 2):37-46._x000D_ 2: Tsygankov AY, Mahajan S, Fincke JE, Bolen JB. Specific association of tyrosine-phosphorylated c-Cbl with Fyn tyrosine kinase in T cells J Biol Chem. 1996 Oct 25;271(43):27130-7._x000D_ 3: Liu CS, Yang-Yen HF, Suen CS, Hwang MJ, Yen JJ. Cbl-mediated K63-linked ubiquitination of JAK2 enhances JAK2 phosphorylation and signal transduction Sci Rep. 2017 Jul 4;7(1):4613._x000D_ 4: Maulik G, Madhiwala P, Brooks S, Ma PC, Kijima T, Tibaldi EV, Schaefer E, Parmar K, Salgia R. Activated c-Met signals through PI3K with dramatic effects on cytoskeletal functions in small cell lung cancer J Cell Mol Med. 2002 Oct-Dec;6(4):539-53._x000D_ 5: Song X, Akasaka H, Wang H, Abbasgholizadeh R, Shin JH, Zang F, Chen J, Logsdon CD, Maitra A, Bean AJ, Wang H. Hematopoietic progenitor kinase 1 down-regulates the oncogenic receptor tyrosine kinase AXL in pancreatic cancer J Biol Chem. 2020 Feb 21;295(8):2348-2358._x000D_ 6: Li XQ, Xing T, Du D. Identification of Top-ranked Proteins within a Directional Protein Interaction Network using the PageRank Algorithm: Applications in Humans and Plants Curr Issues Mol Biol. 2016;20:13-28. Epub 2015 Dec 4._x000D_ 7: Desai SS, Kharade SS, Parekh VI, Iyer S, Agarwal SK. Pro-oncogenic Roles of HLXB9 Protein in Insulinoma Cells through Interaction with Nono Protein and Down-regulation of the c-Met Inhibitor Cblb (Casitas B-lineage Lymphoma b) J Biol Chem. 2015 Oct 16;290(42):25595-608._x000D_ 8: Tan YC, Mirzapoiazova T, Won BM, Zhu L, Srivastava MK, Vokes EE, Husain AN, Batra SK, Sharma S, Salgia R. Differential responsiveness of MET inhibition in non-small-cell lung cancer with altered CBL Sci Rep. 2017 Aug 23;7(1):9192._x000D_ 9: Duan L, Raja SM, Chen G, Virmani S, Williams SH, Clubb RJ, Mukhopadhyay C, Rainey MA, Ying G, Dimri M, Chen J, Reddi AL, Naramura M, Band V, Band H. Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration J Biol Chem. 2011 Jan 7;286(1):620-33._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/29945960">10: Hong SY, Kao YR, Lee TC, Wu CW. Upregulation of E3 Ubiquitin Ligase CBLC Enhances EGFR Dysregulation and Signaling in Lung Adenocarcinoma Cancer Res. 2018 Sep 1;78(17):4984-4996. </a>_x000D_ _x000D_ <strong>Products Related to Phospho-c-Cbl (Tyr774) Rabbit Antibody APC Conjugate can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>