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SMARCA2 ligand-13 PYR-Pip-spiro[3.3]heptane-acid

Selected Variant

HY-169490

Size: 1 Each

SMARCA2 ligand-13 PYR-Pip-spiro[3.3]heptane-acid is a conjugate generated by linking a target protein ligand to a linker (HY-169489). SMARCA2 ligand-13 PYR-Pip-spiro[3.3]heptane-acid can be used in the synthesis of PROTACs (e.g. PROTAC SMARCA2 degrader-21 (HY-169272) ).

Product Specifications

UNSPSC

12352005

Target

Target Protein Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/target-protein-ligand-linker-conjugates-4.html

Smiles

O=C(O)C1CC2(CC(C2)N3CCC(CC3)C4=NC(N5CCN6C7=CC(C8=C(C=CC=C8)O)=NN=C7NC[C@H]6C5)=NC=C4)C1

Molecular Formula

C32H38N8O3

Molecular Weight

582.70

References & Citations

[1]Zhang Y, et al., Smarca degraders and uses thereof. WO2023278402. WIPO, 2022-06-28

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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