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LONP1-IN-2

LONP1-IN-2 (Compound 9e) is a potent and selective LONP1 inhibitor with an IC50 value of 0.093 μM. LONP1-IN-2 can be used in research of cancer[1][2].

Product Specifications

CAS Number

2729981-17-1

UNSPSC

12352005

Target

Phosphatase; Proteasome

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/lonp1-in-2.html

Concentration

10mM

Purity

99.74

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C)C[C@@H](B(O)O)NC([C@@H](CCCC)NC(C1=NC=CN=C1)=O)=O

Molecular Formula

C16H27BN4O4

Molecular Weight

350.22

References & Citations

[1]Kingsley LJ, et, al. Structure-Based Design of Selective LONP1 Inhibitors for Probing In Vitro Biology. J Med Chem. 2021 Apr 22;64 (8) :4857-4869.|[2]You H, et al. Epstein-Barr virus-driven cardiolipin synthesis sustains metabolic remodeling during B cell transformation. Sci Adv. 2025 Jan 31;11 (5) :eadr8837.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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