LONP1-IN-2
LONP1-IN-2 (Compound 9e) is a potent and selective LONP1 inhibitor with an IC50 value of 0.093 μM. LONP1-IN-2 can be used in research of cancer[1][2].
Product Specifications
CAS Number
2729981-17-1
UNSPSC
12352005
Target
Phosphatase; Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lonp1-in-2.html
Concentration
10mM
Purity
99.74
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C)C[C@@H](B(O)O)NC([C@@H](CCCC)NC(C1=NC=CN=C1)=O)=O
Molecular Formula
C16H27BN4O4
Molecular Weight
350.22
References & Citations
[1]Kingsley LJ, et, al. Structure-Based Design of Selective LONP1 Inhibitors for Probing In Vitro Biology. J Med Chem. 2021 Apr 22;64 (8) :4857-4869.|[2]You H, et al. Epstein-Barr virus-driven cardiolipin synthesis sustains metabolic remodeling during B cell transformation. Sci Adv. 2025 Jan 31;11 (5) :eadr8837.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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