Anti-Mouse TIGIT Antibody (1G9)
Anti-Mouse TIGIT Antibody (1G9) is a mouse-derived agonistic TIGIT IgG1 κ type antibody. Anti-Mouse TIGIT Antibody (1G9) blocks CD155 binding to TIGIT. Anti-Mouse TIGIT Antibody (1G9) shows potent anti-infection and anti-immune effects in septic and experimental autoimmune encephalomyelitis[1][2][3].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352203
Target
Transmembrane Glycoprotein
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/anti-mouse-tigit-antibody-1g9.html
Purity
99.23
Solubility
10 mM in DMSO
Smiles
[Anti-MouseTIGITAntibody(1G9)]
Molecular Weight
(150 kDa)
References & Citations
[1]Schorer M, et al. TIGIT limits immune pathology during viral infections. Nat Commun. 2020 Mar 9;11 (1) :1288.|[2]Zhang W, et al. TIGIT modulates sepsis-induced immune dysregulation in mice with preexisting malignancy. JCI Insight. 2021 Jun 8;6 (11) :e139823.|[3]Dixon KO, et al. Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor Immunity. J Immunol. 2018 Apr 15;200 (8) :3000-3007.
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4°C for 2 years, do not freeze
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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