5-Methoxy cytidine

5-Methoxy cytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

Product Specifications

CAS Number

[37805-90-6]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/5-methoxy-cytidine.html

Solubility

10 mM in DMSO

Smiles

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)C(OC)=C2)=O)O1

Molecular Formula

C10H15N3O6

Molecular Weight

273.24

Precautions

P264-P270-P280-P302+P352-P330-P362+P364-P501

References & Citations

[1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3 (11) :1062-8.