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4,5-Dichloro-3H-1,2-dithiol-3-one

4,5-Dichloro-3H-1,2-dithiol-3-one (Dichloro-1,2-dithiacyclopentenone) is an E. coli FabH inhibitor (IC50: 2.9 µM) . 4,5-Dichloro-3H-1,2-dithiol-3-one can be used as a slimicide in the manufacture of food-contact paper and paperboard [1][2].

Product Specifications

CAS Number

1192-52-5

Product Name Alternative

Dichloro-1,2-dithiacyclopentenone

UNSPSC

12352200

Hazard Statement

H301, H315, H335, H400

Target

Bacterial

Type

Biochemical Assay Reagents

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/4-5-dichloro-3h-1-2-dithiol-3-one.html

Purity

98.0

Smiles

ClC(C1=O)=C(SS1)Cl

Molecular Formula

C3Cl2OS2

Molecular Weight

187.07

Precautions

H301, H315, H335, H400

References & Citations

[1]Song X, et al. Synthesis and antibacterial activity of cinnamaldehyde acylhydrazone with a 1,4-benzodioxan fragment as a novel class of potent β-ketoacyl-acyl carrier protein synthase III (FabH) inhibitor. Chem Pharm Bull (Tokyo) . 2014;62 (11) :1110-8.|[2]Mary S. Wolfe, et al. Chapter. National Toxicology Program. Book. Toxicology and Regulatory Process. 2006. Pages. 32

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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