4,5-Dichloro-3H-1,2-dithiol-3-one
4,5-Dichloro-3H-1,2-dithiol-3-one (Dichloro-1,2-dithiacyclopentenone) is an E. coli FabH inhibitor (IC50: 2.9 µM) . 4,5-Dichloro-3H-1,2-dithiol-3-one can be used as a slimicide in the manufacture of food-contact paper and paperboard [1][2].
Product Specifications
CAS Number
[1192-52-5]
Product Name Alternative
Dichloro-1,2-dithiacyclopentenone
UNSPSC
12352200
Hazard Statement
H301, H315, H335, H400
Target
Bacterial
Type
Biochemical Assay Reagents
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/4-5-dichloro-3h-1-2-dithiol-3-one.html
Purity
98.0
Smiles
ClC(C1=O)=C(SS1)Cl
Molecular Formula
C3Cl2OS2
Molecular Weight
187.07
Precautions
H301, H315, H335, H400
References & Citations
[1]Song X, et al. Synthesis and antibacterial activity of cinnamaldehyde acylhydrazone with a 1,4-benzodioxan fragment as a novel class of potent β-ketoacyl-acyl carrier protein synthase III (FabH) inhibitor. Chem Pharm Bull (Tokyo) . 2014;62 (11) :1110-8.|[2]Mary S. Wolfe, et al. Chapter. National Toxicology Program. Book. Toxicology and Regulatory Process. 2006. Pages. 32
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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