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GPR55 agonist 3

GPR55 agonist 3 (Compound 26) is a GPR55 agonist (EC50: 0.239 nM, and 1.76 nM for hGPR55 and rGPR55) . GPR55 agonist 3 induces β-arrestin recruitment to human GPR55 (EC50: 6.2 nM) [1].

Product Specifications

CAS Number

3006105-44-5

UNSPSC

12352005

Target

GPR55

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/gpr55-agonist-3.html

Purity

99.17

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

FC(F)(F)CC1=CN=CC(C2=CN=C(N[C@@H](C3=CC=C(F)C=C3)C)C=N2)=C1

Molecular Formula

C19H16F4N4

Molecular Weight

376.35

References & Citations

[1]Hewer RC, et al. Discovery and Characterization of Novel CNS-Penetrant GPR55 Agonists. J Med Chem. 2023 Sep 28;66 (18) :12858-12876.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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