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ND-322 (hydrochloride)

ND-322 hydrochloride is a potent and selective water-soluble gelatinase inhibitor. ND-322 hydrochloride reduces melanoma tumor growth and delays metastatic dissemination[1][2].

Product Specifications

CAS Number

1333379-23-9

UNSPSC

12352005

Target

MMP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nd-322-hydrochloride.html

Purity

98.14

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NC1=CC=C(C=C1)OC2=CC=C(C=C2)S(=O)(CC3SC3)=O.Cl

Molecular Formula

C15H16ClNO3S2

Molecular Weight

357.88

References & Citations

[1]Gooyit M, et, al. Selective water-soluble gelatinase inhibitor prodrugs. J Med Chem. 2011 Oct 13;54 (19) :6676-90.|[2]Marusak C, et, al. The thiirane-based selective MT1-MMP/MMP2 inhibitor ND-322 reduces melanoma tumor growth and delays metastatic dissemination. Pharmacol Res. 2016 Nov;113 (Pt A) :515-520.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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