ND-322 (hydrochloride)
ND-322 hydrochloride is a potent and selective water-soluble gelatinase inhibitor. ND-322 hydrochloride reduces melanoma tumor growth and delays metastatic dissemination[1][2].
Product Specifications
CAS Number
[1333379-23-9]
UNSPSC
12352005
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nd-322-hydrochloride.html
Purity
98.14
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC1=CC=C(C=C1)OC2=CC=C(C=C2)S(=O)(CC3SC3)=O.Cl
Molecular Formula
C15H16ClNO3S2
Molecular Weight
357.88
References & Citations
[1]Gooyit M, et, al. Selective water-soluble gelatinase inhibitor prodrugs. J Med Chem. 2011 Oct 13;54 (19) :6676-90.|[2]Marusak C, et, al. The thiirane-based selective MT1-MMP/MMP2 inhibitor ND-322 reduces melanoma tumor growth and delays metastatic dissemination. Pharmacol Res. 2016 Nov;113 (Pt A) :515-520.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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