A-1155463
A-1155463, a chemical probe, is a highly potent and selective BCL-XL inhibitor with an EC50 of 70 nM in Molt-4 cell. A-1155463 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
1235034-55-5
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/A-1155463.html
Concentration
10mM
Purity
99.62
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=C(CCCOC2=CC=C(C#CCN(C)C)C=C2F)SC(N3CC4=C(C=CC=C4C(NC5=NC6=CC=CC=C6S5)=O)CC3)=N1)O
Molecular Formula
C35H32FN5O4S2
Molecular Weight
669.79
Precautions
H302, H312, H332
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Bcl-2; Bcl-xL
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![CRTC3 Mouse Monoclonal Antibody [Clone ID: 5G9]](https://cdn.genprice.uk/products/937/68dd189a061270361e8fbe56/imageurl/am06581su-n.webp)
![L1CAM Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2H5]](https://cdn.genprice.uk/products/937/6868c319994c49e6dc3eede6/imageurl/ta500732am.webp)
L1CAM Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2H5]
