Withangulatin A
Product Specifications
UNSPSC Description
Withangulatin A is a selective cyclooxygenase-2 (COX-2) inhibitor. Withangulatin A can be isolated from Physalis angulata L. Withangulatin A has anti-tumor, trypanocidal activity and anti-inflammatory function[1].
Target Antigen
COX; Parasite
Type
Natural Products
Related Pathways
Anti-infection;Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/withangulatin-a.html
Purity
99.76
Solubility
DMSO : 3 mg/mL (ultrasonic;warming)
Smiles
C[C@]12[C@@]3([C@H](C=CC2=O)O)[C@](C[C@]4([H])[C@]1([H])CC[C@]5([C@]4([C@H](C=C5[C@@H]([C@@]6([H])CC(C)=C(C(O6)=O)C)C)OC(C)=O)O)C)([H])O3
Molecular Weight
526.62
References & Citations
[1] Lijuan Sun, et al. Anti-inflammatory function of Withangulatin A by targeted inhibiting COX-2 expression via MAPK and NF-kappaB pathways. J Cell Biochem. 2010 Feb 15;109(3):532-41.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N10303/Withangulatin-A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N10303/Withangulatin-A-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
120824-03-5
Available Sizes
Curated Selection
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