Gypsogenic acid

Gypsogenic acid is a triterpenoid acid that can be isolated from Miconia stenostachya and has antibacterial and trypanoidal activities. The MICs values of Gypsogenic acid for the oral bacterial pathogens Enterococcus faecalis, Streptococcus salivarius, Streptococcus haematococcus, Streptococcus mutans and sobrinus were 50-200 μg/mL. Gypsogenic acid can induce blood cortensite cleavage in isolated mice with IC50 56.6 μM[1][2].

Product Specifications

CAS Number

[5143-05-5]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; Parasite

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/gypsogenic-acid.html

Purity

99.9

Smiles

C[C@@]12C([C@@]3([H])[C@@](CC2)(CCC(C)(C3)C)C(O)=O)=CC[C@@]4([H])[C@]1(CC[C@]5([H])[C@@]4(CC[C@@H]([C@@]5(C)C(O)=O)O)C)C

Molecular Formula

C30H46O5

Molecular Weight

486.68

Precautions

H302, H315, H319, H335

References & Citations

[1]Scalon Cunha LC, et al. Antibacterial activity of triterpene acids and semi-synthetic derivatives against oral pathogens. Z Naturforsch C J Biosci. 2007 Sep-Oct;62 (9-10) :668-72.|[2]Cunha WR, et al. In vitro trypanocidal activity of triterpenes from miconia species. Planta Med. 2003 May;69 (5) :470-2.