MHY-1685

MHY-1685, a novel mammalian target of rapamycin (mTOR) inhibitor, provides opportunities to improve hCSC-based myocardial regeneration.

Product Specifications

CAS Number

[27406-31-1]

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

MTOR

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mhy-1685.html

Concentration

10mM

Purity

99.84

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

O=C(NC(NC/1=O)=O)C1=C/C2=CC=C(O)C=C2

Molecular Formula

C11H8N2O4

Molecular Weight

232.19

Precautions

H302, H312, H332

References & Citations

[1]Park JH, et al. Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair. Exp Mol Med. 2021 Sep;53 (9) :1423-1436.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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