Human CD63 Full Length Protein, Flag, His Tag (Detergent)
Human CD63 Full Length Protein, Flag, His Tag (CD3-H55D3) is expressed from Baculovirus-Insect cells. It contains AA Ala 2 - Met 238 (Accession # P08962) .
Product Specifications
Background
Functions as a cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
Specifications
This protein carries flag tag at the N-terminus and polyhistidine tag at the C-terminus. The protein has a calculated MW of 29.6 kDa.
Accession Number
P08962
Expression Region
Ala 2 - Met 238
Host
Insect Cells
Target
CD63
Conjugation
Unconjugated
Tag
N-Flag & C-10xHis
Source
Human
Stability
● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Endotoxin
1.0 EU per μg
Bioactivity
Immobilized Human CD63 Full Length Protein, Flag,His Tag (Cat. No. CD3-H55D3) at 1 μg/mL (100 μL/well) can bind Anti-CD63 Antibody with a linear range of 1-31 ng/mL (QC tested).
Format
Liquid
Buffer
50 mM HEPES, 150 mM NaCl, DDM, pH7.5, CHS
Additives
Glycerol
Molecular Weight
29.6 kDa
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
20ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CD3-H55D3.pdf
Species
Human
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